Category: Argentina’s Local Crop Biotechnology Developments: Why Have They Not Reached the Market Yet?

  • ormulation technology for stabilized lipid-based nanoparticles (LNPs)

    This was largely made possible by major advances in the formulation technology for stabilized lipid-based nanoparticles (LNPs). Design of the cationic ionizable lipids, which are a key component of the LNP formulations, with an acid dissociation constant (pKa) close to the early endosomal pH, would not only ensure effective encapsulation of mRNA into the stabilized…

  • Fusogenic Viral Protein-Based Near-Infrared Active Nanocarriers for Biomedical

    As a proof of concept, we bioengineered the vesicular stomatitis virus glycoprotein (VSV-G)-based near-infrared (NIR) active viral nanoconstructs (NAVNs) encapsulating indocyanine green dye (ICG) for NIR bioimaging. NAVNs are spherical in size and have the intrinsic cellular-fusogenic properties of VSV-G. Further, the NIR imaging displaying higher fluorescence intensity in NAVNs treated cells suggests enhanced cellular…

  • Argentina’s Local Crop Biotechnology Developments: Why Have They Not Reached the Market Yet?

    Argentina’s Local Crop Biotechnology Developments: Why Have They Not Reached the Market Yet?

    Plant biotechnology in Argentina started at the end of the 1980s, leading to the development of numerous research groups in public institutions and, a decade later, to some local private initiatives. The numerous scientific and technological capacities existing in the country allowed the early constitution in 1991 of a sound genetically modified organisms biosafety regulatory…