Integration of nano- and biotechnology for beta-cell and islet transplantation in type-1 diabetes treatment.

Regenerative drugs utilizing human or porcine β-cells or islets has a wonderful potential to turn out to be a clinically related technique for the therapy of type-1 diabetes. Excessive-resolution imaging of the perform and religion of transplanted porcine pancreatic islets and human stem cell-derived beta cells in giant animals and sufferers for testing superior remedy medicinal merchandise (ATMPs) is a presently unmet want for pre-clinical/medical trials.

The iNanoBIT EU H2020 challenge is growing novel extremely delicate nanotechnology-based imaging approaches permitting for monitoring of survival, engraftment, proliferation, perform and whole-body distribution of the mobile transplants in a porcine diabetes mannequin with glorious translational potential to people. We develop and validate the appliance of single-photon emission computed tomography (SPECT) and optoacoustic imaging applied sciences in a transgenic insulin-deficient pig mannequin to watch transplanted porcine xeno-islets and in vitro differentiated human beta cells.

We’re progressing in producing new transgenic reporter pigs and human-induced pluripotent cell (iPSC) traces for optoacoustic imaging and testing them in transplantable bioartificial islet units. Novel multifunctional nanoparticles have been generated and are being examined for nuclear imaging of islets and beta cells utilizing a brand new, high-resolution SPECT imaging gadget.

EIF2S1 siRNA

20-abx915151
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

EIF2S1 siRNA

20-abx915152
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

EIF2S1 siRNA

20-abx901677
  • EUR 551.00
  • EUR 732.00
  • 15 nmol
  • 30 nmol

EIF2S1 Antibody

1-CSB-PA007523GA01HU
  • EUR 597.00
  • EUR 333.00
  • 150ul
  • 50ul
Description: A polyclonal antibody against EIF2S1. Recognizes EIF2S1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF

EIF2S1 Antibody

1-CSB-PA007523LA01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against EIF2S1. Recognizes EIF2S1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

EIF2S1 Antibody

1-CSB-PA002295
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against EIF2S1. Recognizes EIF2S1 from Human, Mouse, Rat, Monkey. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000

EIF2S1 Antibody

47097-100ul 100ul
EUR 252

EIF2S1 antibody

10R-1784 100 ul
EUR 322
Description: Mouse monoclonal EIF2S1 antibody

EIF2S1 antibody

10R-3949 100 ul
EUR 691
Description: Mouse monoclonal EIF2S1 antibody

EIF2S1 antibody

10R-3952 100 ul
EUR 691
Description: Mouse monoclonal EIF2S1 antibody

EIF2S1 antibody

10R-3954 100 ul
EUR 691
Description: Mouse monoclonal EIF2S1 antibody

EIF2S1 antibody

70R-17043 50 ul
EUR 435
Description: Rabbit polyclonal EIF2S1 antibody

EIF2S1 antibody

10R-1275 100 ug
EUR 512
Description: Mouse monoclonal EIF2S1 antibody

EIF2S1 antibody

70R-1419 100 ug
EUR 377
Description: Rabbit polyclonal EIF2S1 antibody raised against the C terminal of EIF2S1

EIF2S1 antibody

70R-4888 50 ug
EUR 467
Description: Rabbit polyclonal EIF2S1 antibody raised against the N terminal of EIF2S1

EIF2S1 antibody

70R-49694 100 ul
EUR 287
Description: Purified Polyclonal EIF2S1 antibody

EIF2S1 antibody

70R-49695 100 ul
EUR 244
Description: Purified Polyclonal EIF2S1 antibody

Anti-EIF2S1 Antibody

PA2029 100ug/vial
EUR 334

EIF2S1 Rabbit pAb

A0764-100ul 100 ul
EUR 308

EIF2S1 Rabbit pAb

A0764-200ul 200 ul
EUR 459

EIF2S1 Rabbit pAb

A0764-20ul 20 ul
EUR 183

EIF2S1 Rabbit pAb

A0764-50ul 50 ul
EUR 223

EIF2S1 Blocking Peptide

20-abx062570
  • EUR 272.00
  • EUR 411.00
  • 1 mg
  • 5 mg

EIF2S1 (pS51) Antibody

20-abx009744
  • EUR 314.00
  • EUR 467.00
  • EUR 203.00
  • 100 ul
  • 200 ul
  • 30 ul

EIF2S1 (pS49) Antibody

20-abx000389
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul

EIF2S1 (pS51) Antibody

20-abx000390
  • EUR 495.00
  • EUR 704.00
  • EUR 356.00
  • 100 ul
  • 200 ul
  • 50 ul

Anti-EIF2S1 antibody

STJ23509 100 µl
EUR 277

anti- EIF2S1 antibody

FNab02699 100µg
EUR 505.25
Description: Antibody raised against EIF2S1

EIF2S1 Conjugated Antibody

C47097 100ul
EUR 397

Anti-EIF2S1 antibody

PAab02699 100 ug
EUR 355

pOTB7-EIF2S1 Plasmid

PVTB01152-1 2 ug
EUR 356

EIF2S1 Blocking Peptide

33R-7946 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of EIF2S1 antibody, catalog no. 70R-1419

EIF2S1 Blocking Peptide

33R-9903 100 ug
EUR 180
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of EIF2S1 antibody, catalog no. 70R-4888

Rat EIF2S1 shRNA Plasmid

20-abx985838
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

EIF2S1 (pS51) Blocking Peptide

20-abx062569
  • EUR 314.00
  • EUR 509.00
  • 1 mg
  • 5 mg

Human EIF2S1 shRNA Plasmid

20-abx951360
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Mouse EIF2S1 shRNA Plasmid

20-abx970140
  • EUR 801.00
  • EUR 1121.00
  • 150 µg
  • 300 µg

Phospho-EIF2S1 (Ser51) Antibody

CSB-PA285504-
EUR 335
Description: A polyclonal antibody against Phospho-EIF2S1 (Ser51). Recognizes Phospho-EIF2S1 (Ser51) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-EIF2S1 (Ser51) Antibody

CSB-PA285504-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-EIF2S1 (Ser51). Recognizes Phospho-EIF2S1 (Ser51) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

EIF2S1 (Ab-51) Antibody

CSB-PA447773-
EUR 335
Description: A polyclonal antibody against EIF2S1 (Ab-51). Recognizes EIF2S1 (Ab-51) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

EIF2S1 (Ab-51) Antibody

CSB-PA447773-100ul 100ul
EUR 316
Description: A polyclonal antibody against EIF2S1 (Ab-51). Recognizes EIF2S1 (Ab-51) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

Phospho-EIF2S1 (Ser49) Antibody

CSB-PA279986-
EUR 335
Description: A polyclonal antibody against Phospho-EIF2S1 (Ser49). Recognizes Phospho-EIF2S1 (Ser49) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-EIF2S1 (Ser49) Antibody

CSB-PA279986-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-EIF2S1 (Ser49). Recognizes Phospho-EIF2S1 (Ser49) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

EIF2S1 Antibody, HRP conjugated

1-CSB-PA007523LB01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against EIF2S1. Recognizes EIF2S1 from Human. This antibody is HRP conjugated. Tested in the following application: ELISA

EIF2S1 Antibody, FITC conjugated

1-CSB-PA007523LC01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against EIF2S1. Recognizes EIF2S1 from Human. This antibody is FITC conjugated. Tested in the following application: ELISA

EIF2S1 Antibody, Biotin conjugated

1-CSB-PA007523LD01HU
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against EIF2S1. Recognizes EIF2S1 from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA

Phospho-EIF2S1 (S51) Antibody

1-CSB-PA000518
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against Phospho-EIF2S1 (S51). Recognizes Phospho-EIF2S1 (S51) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IHC, ELISA;WB:1/500-1/2000.IHC:1/100-1/300.ELISA:1/10000

Mouse Eif2s1 ELISA KIT

ELI-42145m 96 Tests
EUR 865

Chicken EIF2S1 ELISA KIT

ELI-31510c 96 Tests
EUR 928

Bovine EIF2S1 ELISA KIT

ELI-20514b 96 Tests
EUR 928

Human EIF2S1 ELISA KIT

ELI-20515h 96 Tests
EUR 824

EIF2S1 ELISA KIT|Human

EF009335 96 Tests
EUR 689

Anti-EIF2S1 (3H12-C11)

YF-MA10267 100 ug
EUR 363
Description: Mouse monoclonal to EIF2S1

EIF2S1 Recombinant Protein (Mouse)

RP131255 100 ug Ask for price

EIF2S1 Recombinant Protein (Human)

RP056361 100 ug Ask for price

EIF2S1 Recombinant Protein (Rat)

RP199328 100 ug Ask for price

EIF2S1 protein (His tag)

80R-3334 50 ug
EUR 257
Description: Purified recombinant EIF2S1 protein (His tag)

EIF2S1 protein (His tag)

80R-1344 50 ug
EUR 397
Description: Purified recombinant Human EIF2S1 protein

Anti-Phospho-EIF2S1-(S49) antibody

STJ22112 100 µl
EUR 393

Anti-Phospho-EIF2S1-(S51) antibody

STJ22113 100 µl
EUR 393

Anti-Phospho-EIF2S1-(S51) antibody

STJ116376 100 µl
EUR 393

Eif2s1 ORF Vector (Rat) (pORF)

ORF066444 1.0 ug DNA
EUR 506

Eif2s1 ORF Vector (Mouse) (pORF)

ORF043753 1.0 ug DNA
EUR 506

EIF2S1 ORF Vector (Human) (pORF)

ORF018788 1.0 ug DNA
EUR 405

Eif2s1 sgRNA CRISPR Lentivector set (Mouse)

K3405701 3 x 1.0 ug
EUR 339

EIF2S1 sgRNA CRISPR Lentivector set (Human)

K0666401 3 x 1.0 ug
EUR 339

Eif2s1 sgRNA CRISPR Lentivector set (Rat)

K6880001 3 x 1.0 ug
EUR 339

Phospho-EIF2S1 (S51) recombinant monoclonal antibody

A5941 100ul X 3
EUR 681
Description: A recombinant monoclonal antibody from rabbit against human Phospho-EIF2S1 (S51) for WB,ELISA

Anti-Phospho-EIF2S1 (S51) Rabbit Monoclonal Antibody

P04387 100ug/vial
EUR 397
Description: Rabbit Monoclonal Phospho-EIF2S1 (S51) Antibody. Validated in Flow Cytometry, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Eif2s1 sgRNA CRISPR Lentivector (Mouse) (Target 1)

K3405702 1.0 ug DNA
EUR 154

Eif2s1 sgRNA CRISPR Lentivector (Mouse) (Target 2)

K3405703 1.0 ug DNA
EUR 154

Eif2s1 sgRNA CRISPR Lentivector (Mouse) (Target 3)

K3405704 1.0 ug DNA
EUR 154

EIF2S1 sgRNA CRISPR Lentivector (Human) (Target 1)

K0666402 1.0 ug DNA
EUR 154

EIF2S1 sgRNA CRISPR Lentivector (Human) (Target 2)

K0666403 1.0 ug DNA
EUR 154

EIF2S1 sgRNA CRISPR Lentivector (Human) (Target 3)

K0666404 1.0 ug DNA
EUR 154

Eif2s1 sgRNA CRISPR Lentivector (Rat) (Target 1)

K6880002 1.0 ug DNA
EUR 154

Eif2s1 sgRNA CRISPR Lentivector (Rat) (Target 2)

K6880003 1.0 ug DNA
EUR 154

Eif2s1 sgRNA CRISPR Lentivector (Rat) (Target 3)

K6880004 1.0 ug DNA
EUR 154

Eif2s1 3'UTR GFP Stable Cell Line

TU253876 1.0 ml Ask for price

Eif2s1 3'UTR Luciferase Stable Cell Line

TU203876 1.0 ml Ask for price

Eif2s1 3'UTR GFP Stable Cell Line

TU155709 1.0 ml Ask for price

Eif2s1 3'UTR Luciferase Stable Cell Line

TU105709 1.0 ml Ask for price

EIF2S1 3'UTR Luciferase Stable Cell Line

TU006718 1.0 ml
EUR 2333

EIF2S1 3'UTR GFP Stable Cell Line

TU056718 1.0 ml
EUR 2333

EIF2S1 Protein Vector (Mouse) (pPB-C-His)

PV175010 500 ng
EUR 603

EIF2S1 Protein Vector (Mouse) (pPB-N-His)

PV175011 500 ng
EUR 603

EIF2S1 Protein Vector (Mouse) (pPM-C-HA)

PV175012 500 ng
EUR 603

EIF2S1 Protein Vector (Mouse) (pPM-C-His)

PV175013 500 ng
EUR 603

EIF2S1 Protein Vector (Human) (pPB-C-His)

PV075149 500 ng
EUR 552

EIF2S1 Protein Vector (Human) (pPB-N-His)

PV075150 500 ng
EUR 552

EIF2S1 Protein Vector (Human) (pPM-C-HA)

PV075151 500 ng
EUR 552

EIF2S1 Protein Vector (Human) (pPM-C-His)

PV075152 500 ng
EUR 552

EIF2S1 Protein Vector (Rat) (pPB-C-His)

PV265774 500 ng
EUR 603

EIF2S1 Protein Vector (Rat) (pPB-N-His)

PV265775 500 ng
EUR 603

EIF2S1 Protein Vector (Rat) (pPM-C-HA)

PV265776 500 ng
EUR 603

EIF2S1 Protein Vector (Rat) (pPM-C-His)

PV265777 500 ng
EUR 603

Recombinant Human EIF2S1 Protein, His, E.coli-10ug

QP11766-10ug 10ug
EUR 201

Recombinant Human EIF2S1 Protein, His, E.coli-1mg

QP11766-1mg 1mg
EUR 5251

General, the mixed multidisciplinary experience of the challenge companions permits progress in direction of creating a lot wanted technological toolboxes for the xenotransplantation and ATMP subject, and thus reinforces the European healthcare provide chain for regenerative medicinal merchandise.