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Resolving the formidable barrier of oxygen transferring rate (OTR) in ultrahigh-titer bioconversion/biocatalysis by a sealed-oxygen supply biotechnology (SOS).

The vital situation within the competitiveness between bioengineering and chemical engineering is the merchandise titer and the amount productiveness. Essentially the most direct and efficient method normally employs high-density biocatalyst, whereas the weakened mass switch and evoked foam downside accompany ultrahigh-density biocatalyst loading and substrate/product titer. In high-density obligate cardio bioconversion, oxygen as electron acceptor…